Understanding, Monitoring, and Modulating Biological Systems with Ultrasound
We integrate physical acoustics, mathematical modeling, and mechanobiology to understand ultrasound-tissue interactions and engineer intelligent platforms for multi-scale drug delivery, immune cell modulation, and real-time monitoring of therapeutic response.

Advancing Patient-Specific Noninvasive Therapies
To establish patient-specific ultrasound technologies that enable precise, noninvasive interventions to improve the treatment of brain diseases.
Discover the Mechanisms

Ultrasound Biophysics & Wave Propagation
Integrating multiscale physics, Fourier acoustics, and mathematical modeling to map acoustic fields.

Biomolecular Transport
Uncovering the physical mechanisms governing transport across vascular, cellular, and tissue barriers.

Cellular and Vascular Mechanobiology
Investigating how acoustic forces regulate vascular biology, mechanosensitive signaling, and immune-cell function.

Quantitative Immune-Cell Imaging
Understanding and exploiting intracellular microbubble dynamics to image immune-cell trafficking in vivo.
Engineer the Solution

Acoustic Holography & Beamforming
Synthesizing complex 3D acoustic fields for targeted noninvasive therapy.

Image-Guided Focused Ultrasound
Developing noninvasive platforms for real-time acoustic and thermal monitoring.

AI & Closed-Loop Control
Developing data-driven and predictive algorithms for real-time control of therapeutic ultrasound.

Targeted Delivery & Liquid Biopsy
Engineering acoustic strategies for targeted therapeutic delivery and biomarker release across biological barriers.
Revealing New Mechanisms, Enabling New Therapies

A Team of Scientists, Engineers, and Innovators
The Ultrasound Biophysics and Bioengineering Laboratory brings together scientists, engineers and trainees united by a common goal: understanding and controlling biological systems to improve human health. Our interdisciplinary environment fosters discovery, innovation, translation, and the development of future scientific leaders.
From Discovery to Translation
Translating biomedical ultrasound research through people, technologies, and collaborative initiatives.

Training the Next Generation
Synthesizing complex 3D acoustic fields for targeted noninvasive therapy.

From Discovery to Translation
Developing noninvasive platforms for real-time acoustic and thermal monitoring.

Building a Collaborative Ultrasound Community
Developing data-driven and predictive algorithms for real-time control of therapeutic ultrasound.






