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Ultrasound Biophysics & Bioengineering Lab

MISSION

Understanding, Monitoring, and Modulating Biological Systems with Ultrasound

We integrate physical acoustics, mathematical modeling, and mechanobiology to understand ultrasound-tissue interactions and engineer intelligent platforms for multi-scale drug delivery, immune cell modulation, and real-time monitoring of therapeutic response.

VISION

Advancing Patient-Specific Noninvasive Therapies

To establish patient-specific ultrasound technologies that enable precise, noninvasive interventions to improve the treatment of brain diseases.

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Biology
Physics
Engineering
SCIENCE

Discover the Mechanisms

Ultrasound Biophysics & Wave Propagation

Ultrasound Biophysics & Wave Propagation

Integrating multiscale physics, Fourier acoustics, and mathematical modeling to map acoustic fields.

Biomolecular Transport

Biomolecular Transport

Uncovering the physical mechanisms governing transport across vascular, cellular, and tissue barriers.

Cellular and Vascular Mechanobiology

Cellular and Vascular Mechanobiology

Investigating how acoustic forces regulate vascular biology, mechanosensitive signaling, and immune-cell function.

Quantitative Immune-Cell Imaging

Quantitative Immune-Cell Imaging

Understanding and exploiting intracellular microbubble dynamics to image immune-cell trafficking in vivo.

TECHNOLOGY

Engineer the Solution

Acoustic Holography & Beamforming

Acoustic Holography & Beamforming

Synthesizing complex 3D acoustic fields for targeted noninvasive therapy.

Image-Guided Focused Ultrasound

Image-Guided Focused Ultrasound

Developing noninvasive platforms for real-time acoustic and thermal monitoring.

AI & Closed-Loop Control

AI & Closed-Loop Control

Developing data-driven and predictive algorithms for real-time control of therapeutic ultrasound.

Targeted Delivery & Liquid Biopsy

Targeted Delivery & Liquid Biopsy

Engineering acoustic strategies for targeted therapeutic delivery and biomarker release across biological barriers.

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PEOPLE

A Team of Scientists, Engineers, and Innovators

The Ultrasound Biophysics and Bioengineering Laboratory brings together scientists, engineers and trainees united by a common goal: understanding and controlling biological systems to improve human health. Our interdisciplinary environment fosters discovery, innovation, translation, and the development of future scientific leaders.

IMPACT

From Discovery to Translation

Translating biomedical ultrasound research through people, technologies, and collaborative initiatives.

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Training the Next Generation

Synthesizing complex 3D acoustic fields for targeted noninvasive therapy.

Side view of two professional virologists in lab coats discussing virus cell on computer screen while one of them sitting in wheelchair

From Discovery to Translation

Developing noninvasive platforms for real-time acoustic and thermal monitoring.

Building a Collaborative Ultrasound Community

Building a Collaborative Ultrasound Community

Developing data-driven and predictive algorithms for real-time control of therapeutic ultrasound.

Join UBBL

Join a Community of Discovery, Innovation, and Impact